发明名称 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA
摘要 PROBLEM TO BE SOLVED: To provide methods of removing potassium in the gastrointestinal tract.SOLUTION: The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and salts of such polymers. Crosslinked cation exchange polymers having beneficial physical properties, including combinations of the particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio are also described. These polymers and compositions are useful to bind potassium in the gastrointestinal tract.SELECTED DRAWING: None
申请公布号 JP2016145256(A) 申请公布日期 2016.08.12
申请号 JP20160095867 申请日期 2016.05.12
申请人 ILYPSA INC 发明人 MANSKY PAUL;DETLEF ALBRECHT;MICHAEL BURDICK;CHANG HAN-TING;CHARMOT DOMINIQUE;CONNOR ERIC;SHERIN HALFON;HUANG I-ZU;LIU MINGJUN;RAMAKRISHNAN CHIDAMBARAM;JONATHAN MILLS;WERNER STRUEVER
分类号 A61K31/78;A61K31/785;A61K31/795;A61K31/80;A61K47/10;A61P3/12;A61P7/00;A61P9/04;A61P13/12 主分类号 A61K31/78
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