| 摘要 |
PURPOSE:A herb such as Polygala senega L or Polygala tenuifolia Wild is used as a starting material to effect a specific extraction or, when necessary, a combination thereof with elution to obtain high-purity saponin used as an antitussive or expectorant in high yield. CONSTITUTION:Root stems of herb such as Polygala senega L or Polygala tenuifolia Wild is treated with a volatile alcohol and/or water to obtain the soluble components, then the solvent is evaporated off to obtain the solid product. Then, the solid product is suspended in water and the suspension is treated with a solvent selected from ether, ethyl acetate, chloroform or hexane to remove the lipid-soluble components, then the treated suspension is extracted with an alcohol selected from butyl alcohol, amyl alcohol and propyl alcohol. The alcohol is evaporated off to dryness from the extract and the resultant solid product is recrystallized out of a solvent selected from ethyl acetate, ether and acetone, then, when needed, the crystals is subjected to column chromatography to extract saponin.
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