发明名称 ANTITUMOR LEUKOCYTE INDUCING MATERIAL
摘要 PURPOSE:The titled material activating leukocyte and introducing powerful tumor damaging cell safely and in good operation efficiency, obtained by adding an antigen existing on the surface of a cell in charge of antitumor immunity or an antibody to receptor to the surface of an insoluble carrier. CONSTITUTION:An antigen existing on the surface of killer T cell, helper T cell, NK cell, K cell, monocyte or macrophage, a cell in charge of antitumor immunity, or an antibody to receptor is fixed to the surface of insoluble carrier preferably by covalent bond to give the aimed material. An anti-idiotype monoclonal antibody to antigen bond site of T cell antigen receptor, etc., are preferable as the antibody. A porous carrier of flat membrane or hollow fiber having 0.1-5 micron pore diameter is preferable as the insoluble carrier.
申请公布号 JPS6330500(A) 申请公布日期 1988.02.09
申请号 JP19860172882 申请日期 1986.07.24
申请人 ASAHI CHEM IND CO LTD 发明人 YAMADA KIMIMASA;KAIEDA GOUJI;YAMAWAKI NAOKUNI
分类号 A61K39/395;A61K35/26;A61K39/44;A61M1/36;A61P35/00;C07K16/00;C07K17/02;C07K17/14;C12N5/00;C12N5/07;C12N5/0783;C12N5/0786;C12N5/09;C12P21/00;C12P21/08 主分类号 A61K39/395
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