发明名称 |
2,4 - DIAMINO -S- (SUBSTITUTED) PYRIMIDINES |
摘要 |
<p>Compounds of the formula (II) <CHEM> or a salt, N-oxide or acyl derivative thereof, wherein Y is a group <CHEM> which is optionally substituted; X<1> is an oxygen or sulphur atom, a group CH2, a group S(O)n where n=1 or 2, a group NR<1> wherein R<1> is hydrogen, C1-4 alkyl or a group COR<2> wherein R<2> is hydrogen, C1-4 alkoxy or amino @@@<2> is a six-membered ring containing a nitrogen atom; @@@<3> is a six-membered ring optionally containing a nitrogen atom and the dotted lines represent single or double bonds, have antimicrobial activity. Processes for making these compounds, pharmaceutical compositions containing them and the medical use of the compounds are also disclosed.</p> |
申请公布号 |
AU569468(B2) |
申请公布日期 |
1988.02.04 |
申请号 |
AU19830014105 |
申请日期 |
1983.04.29 |
申请人 |
WELLCOME FOUNDATION LTD., THE, |
发明人 |
SUSAN MARY DALUGE;PAUL MARCEL SKONEZNY;BARBARA ROTH;BARBARA SEAVEY RAUCKMAN |
分类号 |
C07D209/24;C07D215/12;C07D215/22;C07D215/227;C07D217/14;C07D239/48;C07D239/49;C07D333/60;C07D401/06;C07D403/06;C07D405/06;C07D409/06;(IPC1-7):A61K31/505;C07D401/10;C07D403/10;C07D405/10;C07D409/10 |
主分类号 |
C07D209/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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