摘要 |
An improved process for making 6,6-diiodopenicillanic acid, an intermediate for preparation of 6-beta-iodopenicillanic acid, a beta-lactamase inhibitor, which comprises diazotizing 6-beta-aminopenicillanic acid in the presence of iodine, followed by washing the product of said process with an aqueous solution of an alkali metal iodide. |