摘要 |
Intermediates useful for the preparation of 2,4,-diamino-3-oxy-6-piperidyl-pyrimidine or minoxidil are made by oxidizing a compound of the formula <CHEM> wherein R is a C1-4alkyl or phenyl unsubstituted or substituted by up to three C1-4 alkyl substituents, to a compound of the formula <CHEM> with magnesium monoperoxyphthalate. The oxidized product may be converted into minoxidil by known methods. |