发明名称 |
A-acylamino aminoalkyl phophonate angiotensin converting enzyme inhibitors. |
摘要 |
<p>Compounds of the formula <CHEM> wherein X is various amino or imino acids and esters are disclosed. These compounds are useful as anti-hypertensive agents due to their angiotensin converting enzyme inhibition activity and depending upon the definition of X may also be useful as analgesics due to their enkephalinase inhibition activity.</p> |
申请公布号 |
EP0253179(A2) |
申请公布日期 |
1988.01.20 |
申请号 |
EP19870109254 |
申请日期 |
1987.06.26 |
申请人 |
E.R. SQUIBB & SONS, INC. |
发明人 |
KARANEWSKY, DONALD STEVEN;PETRILLO, EDWARD WILLIAM, JR. |
分类号 |
A61P25/04;C07F9/40;C07F9/547;C07F9/572;C07F9/58;C07F9/59;C07F9/62;C07F9/6503;C07F9/6506;C07F9/653;C07F9/6539;C07F9/6558;C07F9/6561;C07F9/38;A61K31/66;A61P9/12 |
主分类号 |
A61P25/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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