摘要 |
PURPOSE:To produce the titled compound useful as a food additive, etc., on an industrial scale at a low cost, by culturing a microbial strain belonging to glutamic acid-producing coryne-form strain resistant to beta-naphthoquinoline and capable of producing L-lysine in a medium and separating the product from the cultured liquid. CONSTITUTION:A microbial strain belonging to glutamic acid-producing coryne- form strain resistant to beta-naphthoquinoline and capable of producing L-lysine [e.g. Corynebacterium glutamicum H-4412 (FERM BP-1069), etc.] is cultured in a medium containing glucose, etc., as carbon source, urea, etc., as nitrogen source and potassium phosphate, etc., as inorganic component. The produced and accumulated L-lysine is separated from the cultured liquid. |