Process for synthesis of glutamic acid from acrylate, amide and synthesis gas

摘要

A process for the synthesis of glutamic acid intermediate from an acrylate, amide and syngas by reacting them in the presence of a catalyst comprising a cobalt-containing compound, a bis-phosphine ligand and a solvent at a pressure of at least 500 psi and a temperature of at least 50 DEG C. and thereafter extracting the glutamic acid.