发明名称 PHENETHANOLAMINE DERIVATIVES
摘要 Compounds of the general formula (I> <IMAGE> (wherein R represents a hydrogen atom or a straight chain C1-3 alkyl group and n is 1 or 2, and physiologically acceptable acid addition salts, solvates and metabolically labile esters thereof) of use in the treatment of heart failure, cardiogenic shock or ischaemic heart disease. Also disclosed are compounds of general formula (XV> <IMAGE> (wherein n is 1 or 2, R<2>, R<3>, R<4> and R<5> each represent a hydrogen atom or a protecting group and R<8> represents a carboxyl group, or a salt or C1-5 alkyl ester thereof) which are of value as intermediates.
申请公布号 PH21664(A) 申请公布日期 1988.01.13
申请号 PH19230000326 申请日期 1985.08.09
申请人 GLAXO GROUP LIMITED 发明人 ROGER FRANK NEWTON;DAVID MIDDLEMISS;ALAN NAYLOR;OLIVE ALWIN MEERHOLZ;CHARLES WILLBE
分类号 A61K31/165;A61P9/00;A61P9/08;C07C67/00;C07C231/00;C07C231/02;C07C231/06;C07C233/12;C07C235/34;C07D263/06 主分类号 A61K31/165
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