发明名称 |
Substituted amino-dihydrooxazoles, -thiazoles and -imidazoles, process for their preparation and pharmaceutical compositions containing them. |
摘要 |
<p>A compound of formula (I): <CHEM> or a pharmaceutically acceptable acid addition salt and/or a pharmaceutically acceptable solvate thereof. wherein R<1> and R<2> each independently represents a hydrogen or halogen atom, a C1-6 alkyl or C1-6 alkoxy group; R<3> and R<4> each independently represents a hydrogen atom or a C1-6 alkyl group; X represents a bond or a moiety CHR<5> wherein R<6> is a group R<3>; and Z represents O or NH; a process for preparing such compounds, a pharmaceutical composition containing such compounds, and the use of such compounds and compositions in medicine.</p> |
申请公布号 |
EP0251453(A2) |
申请公布日期 |
1988.01.07 |
申请号 |
EP19870304019 |
申请日期 |
1987.05.05 |
申请人 |
BEECHAM GROUP PLC |
发明人 |
BEELEY, LEE JAMES BEECHAM PHARMACEUTICALS;BERGE, JOHN BEECHAM PHARMACEUTICALS |
分类号 |
A61K31/415;A61K31/42;A61K31/421;A61K31/425;A61K31/426;A61P3/08;A61P7/02;A61P9/12;A61P25/24;A61P25/26;A61P27/02;A61P27/06;C07D233/50;C07D263/28;C07D277/18;(IPC1-7):C07D233/50 |
主分类号 |
A61K31/415 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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