发明名称 SUBSTITUTED ISOQUINOLINE DERIVATIVES
摘要 A compound of the formula : <CHEM> (wherein R is hydrogen, hydroxy, methoxy, acetoxy, acetoxymethyl or trifluoromethyl; R<1>, R<2>, R<3> and R<4> each is hydrogen, hydroxy, optionally substituted C1-C5 alkoxy, acetoxy, propynyloxy, allyloxy or benzyloxy; or R<2> and R<3> taken together form methylenedioxy; R<5> is hydrogen, hydroxymethyl, C2-C4 alkoxycarbonyl, C2-C5 acyloxymethyl or phthalidyl; and n is 0 or 1 except for the case in which R is methoxy and R<1>, R<2>, R<3>, R<4> and R<5> each is hydrogen) or its pharmaceutically acceptable acid addition salt, being useful as anti-ulcer agents is provided through several routes.
申请公布号 AU7500187(A) 申请公布日期 1988.01.07
申请号 AU19870075001 申请日期 1987.07.01
申请人 SHIONOGI & CO., LTD., 发明人 KENTARO HIRAI;YUKIO MIZUSHIMA
分类号 C07D217/16;A61K31/47;A61K31/472;A61P1/04;C07D217/26;C07D401/12;C07D405/14;C07D491/04;C07D491/056 主分类号 C07D217/16
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