发明名称 |
Naphthalene derivatives, process for their preparation and pharmaceutical compositions containing the same. |
摘要 |
<p>Naphthalene derivative of the formula: <CHEM> wherein Ring A is a substituted or unsubstituted benzene ring; each of R<1> and R<2> is a group of the formula: -OR<5>, -NHR<5> or <CHEM> ; or either one of R<1> and R<2> is a lower alkoxy group and other one is a group of the formula: -OR<5>, -NHR<5> or <CHEM> ; each of R<3> and R<4> is a lower alkoxy group, or one of R<3> and R<4> is a lower alkoxy group and the other is a hydrogen atom; R<5> is a substituted alkyl group, a heterocyclic group, a cycloalkyl group, an alkyl group of at least 5 carbon atoms or alkenyl group; and each of R<6> and R<7> is hydrogen atom or a lower alkyl group and salts thereof are disclosed. Said naphthalene derivative (I) and its salts have excellent hypolipidemic activity and are useful for treatment or prophylaxis of hyperlipidemia and/or arteriosclerosis.</p> |
申请公布号 |
EP0251315(A2) |
申请公布日期 |
1988.01.07 |
申请号 |
EP19870109481 |
申请日期 |
1987.07.01 |
申请人 |
TANABE SEIYAKU CO., LTD. |
发明人 |
IWASAKI, TAMEO;TAKASHIMA, KOHKI |
分类号 |
A61K31/36;A61K31/165;A61K31/235;A61K31/357;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4418;A61K31/535;A61K31/5375;A61P3/04;C07C67/00;C07C69/76;C07C69/767;C07C213/00;C07C231/00;C07C313/00;C07D213/30;C07D213/64;C07D213/65;C07D295/08;C07D295/088;C07D317/70 |
主分类号 |
A61K31/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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