| 摘要 |
<p>The invention comprises naphthalenylsulfonylimidazolidinediones of formula (I) <CHEM> wherein R<4>, R<5>, R<6> and R<7> are hydrogen, halogen, trifluoromethyl, methoxy or dimethylamino and X is oxygen or sulfur and the pharmaceutically acceptable salts thereof, and methods for their preparation. The compounds are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications. Pharmaceutical compositions containing the compounds and methods for manufacturing same are also included in the invention.</p> |
