发明名称 Method of preparing high titer anti-respiratory syncytial virus intravenous immune globulin
摘要 Normal plasma from donors who have not necessarily been vaccinated with a respiratory syncytial virus vaccine can be screened for higher than normal titers of naturally occurring antibody to respiratory syncytial virus (e.g. minimum ELISA titer of at least 1:110,000). Those plasmas with high titers of such antibody can be pooled and fractionated to give hyperimmune globulin. The product may be treated to render it suitable for intravenous injection. Patients with respiratory syncytial virus infection or at risk of such infection, may receive the present product to raise serum antibody titers to respiratory syncytial virus. Resultant product has an ELISA anti-RSV titer of at least about 1:250,000.
申请公布号 US4717766(A) 申请公布日期 1988.01.05
申请号 US19870023339 申请日期 1987.03.09
申请人 MILES LABORATORIES, INC. 发明人 DOBKIN, MILTON B.
分类号 A61K38/00;C07K16/10;(IPC1-7):A61K39/42;A61K39/25 主分类号 A61K38/00
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