FOERFARANDE FOER FRAMSTAELLNING AV MAENNISKO-GAMMA-INTERFERON.

摘要

Process for the production of human gamma-interferon by separating the leukocyte fraction (buffy coat) of blood, removing the erythrocytes, suspending the leukocytes in a suitable nutrient medium, treating the same with a mitogenic agent and separating the liquid containing interferon from the cells which comprises pre-treating the leukocytes with 200-20000 IU/ml. of alpha- or beta-interferon prior to treatment with the mitogenic agent. The advantage of the process is that the gamma-interferon production is increased by 500-1000 %.