发明名称 2-(N-ALKYNYL-N-PHENYLAMINO)IMIDAZOLINE COMPOUNDS
摘要 Substituted 2-(N-alkynyl-N-phenylamino)imidazoline derivatives of the formula I <IMAGE> in which R<1>, R<2>, R<3> and R<4> are defined as in the description, and n can denote the numbers 1, 2 or 3, and their acid addition salts are described. The novel compounds have useful pharmacological and therapeutic properties. The novel compounds are obtained by selective alkynylation on the exocyclic nitrogen atom of the corresponding phenyliminoimidazolidines of the formula II.
申请公布号 ZA8602923(B) 申请公布日期 1987.12.30
申请号 ZA19860002923 申请日期 1986.04.18
申请人 BOEHRINGER INGELHEIM INTERNATIONAL GMBH. 发明人 FRANZ ESSER;HELMUT STAEHLE;HERBERT KOEPPE;WOLFGANG ABELE;LUDWIG PICHLER;WALTER KOBINGER;DIETRICH ARNDTS
分类号 A61K31/415;A61P9/08;A61P9/10;C07D233/50 主分类号 A61K31/415
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