摘要 |
The dosage delivery system of the invention provides for the formulation in the saturated solution to be immediately available for absorption and for the medication in the microcapsule reservoirs to be released at a relatively constant quantity per hour. This ensures substantially linear therapeutic blood levels once state has been achieved. Since steady states are usually achieved within five half-lives, the invention will make the use of potentially toxic drugs (e.g., theophylline) safer and permit less frequent dosage application, thereby ensuring patient compliance. |