发明名称 NOVEL DIPHENIC ACID MONOAMIDES HAVING ACTIVITY AS LEUKOTRIENE ANTAGONISTS,5-LIPOXYGENASE INHIBITORS AND MEDIATOR RELEASE INHIBITORS
摘要 The present invention provides various novel diphenic acid monoamide compounds, novel pharmaceutical compositions and methods of use thereof, as well as novel methods of synthesis therefor. The novel diphenic acid monoamides of the present invention are leukotriene antagonists, 5-lipoxygenase inhibitors, and mediator release inhibitors providing activity useful for treating asthma, allergies, cardiovascular diseases, migraines, and immunoinflammatory conditions.
申请公布号 ZA8603769(B) 申请公布日期 1987.12.30
申请号 ZA19860003769 申请日期 1986.05.20
申请人 WARNER-LAMBERT COMPANY 发明人 JOHN S. KIELY;SUCHIN HUANG
分类号 A61K31/165;A61K31/195;A61K31/335;A61K31/34;A61K31/341;A61K31/357;A61K31/40;A61K31/44;A61K31/4406;A61K31/4418;A61P9/00;A61P11/00;A61P25/04;A61P25/06;A61P29/00;A61P37/00;A61P37/08;A61P43/00;C07C67/00;C07C231/00;C07C233/65;C07C233/75;C07C233/76;C07D207/32;C07D207/325;C07D207/333;C07D213/40;C07D307/52;C07D317/54;C07D317/58 主分类号 A61K31/165
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