发明名称 |
JOINING OF A-CHAIN OF HUMAN RELAIN AND B-CHAIN OF HUMAN RELAXIN |
摘要 |
Production of human relaxin or novel human relaxin analogs by combination of a human relaxin A-chain and B-chain comprising combining the reduced form of the human relaxin A-chain and the reduced form of the human relaxin B-chain in an aqueous medium having a pH of from about 7.0 to 12 at room temperature, under conditions that are mildly denaturing for the relaxin B-chain such that the human relaxin or novel human relaxin analog can be formed. |
申请公布号 |
AU7462087(A) |
申请公布日期 |
1987.12.24 |
申请号 |
AU19870074620 |
申请日期 |
1987.06.23 |
申请人 |
GENENTECH, INC., |
发明人 |
JOHN PERRY BURNIER;PAUL DOUGLAS |
分类号 |
A61K38/22;A61K38/00;A61P15/04;C07K1/02;C07K1/113;C07K14/00;C07K14/575;C07K14/64 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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