发明名称 |
Automatic process for purifying physiologically active substance, apparatus for the same, and carrier with proteinaceous ligand fixed thereto to be used for the same. |
摘要 |
An automatic process for isolating and purifying physiologically active substances contained in large quantities of sample solutions, which comprises the following three steps: (1) filtration (a step for removing microbial cells and other insoluble matters), (2) ultrafiltration (a step for removing impurity having a molecular weight lower than that of the active substance, and concentrating the sample solution), ans (3) affinity chromatography using a carrier with a substance having specific affinity to the active substance fixed thereto (a step for isolating pure product by selective adsorption and elution), an apparatus for use in the same and a carrier employed in the same. |
申请公布号 |
EP0249932(A2) |
申请公布日期 |
1987.12.23 |
申请号 |
EP19870108626 |
申请日期 |
1987.06.16 |
申请人 |
THE GREEN CROSS CORPORATION |
发明人 |
TOSHIHARU, MOTOKUBOTA;HIROSHI, MORISE |
分类号 |
A61K38/00;A61K38/16;A61K38/21;A61K38/22;A61K38/46;C07K1/36;C07K14/525;C07K14/555;C12N9/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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