发明名称 |
Quadroma cells and trioma cells and methods for the production of same |
摘要 |
Antibodies having binding affinity for two desired antigens, hereinafter "recombinant monoclonal antibodies"; recombinant monoclonal antibodies produced by a quadroma cell or a trioma cell; and methods for producing recombinant monoclonal antibodies by means of a quadroma cell or a trioma cell, wherein a quadroma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a hybridoma cell which produces an antibody having specific binding affinity for another desired antigen, and wherein a trioma cell is the fusion product of a hybridoma cell which produces an antibody having specific binding affinity to one desired antigen and a lymphocyte which produces an antibody having specific binding affinity to another desired antigen.
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申请公布号 |
US4714681(A) |
申请公布日期 |
1987.12.22 |
申请号 |
US19840621394 |
申请日期 |
1984.06.18 |
申请人 |
THE BOARD OF REAGENTS, THE UNIVERSITY OF TEXAS SYSTEM CANCER CENTER |
发明人 |
READING, CHRISTOPHER L. |
分类号 |
A61K38/00;C07K16/46;G01N33/577;(IPC1-7):C12N5/00;C12N15/00;C07K15/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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