| 摘要 |
PURPOSE:To enable effective diagnosis of a disorder in various connective tissues, by using a diagnosing drug comprising a monoclonal antibody against keratosulfate. CONSTITUTION:Keratosulfate is used as antigen to prepare a monoclonal antibody used for diagnosis by Caterson, et al's method or the like. A tissue piece picked out of a parson to be inspected as sample is treated by the diagnosing drug thus obtained and disorders in various connective tissues are diagnosed by observing how the diagnosing drug (monoclonal antibody) bonds to the tissue piece. A means to observe the condition of the bonding may employ either direct or indirect method and for the purpose, enzyme antibody method, fluorescent antibody method, ferritin antibody method, fluorescent antibody method, ferritin antibody method, heavy metal labelling method, non label enzyme antibody method and the like can be utilized.
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