摘要 |
PCT No. PCT/FR83/00036 Sec. 371 Date Oct. 26, 1983 Sec. 102(e) Date Oct. 26, 1983 PCT Filed Feb. 25, 1983 PCT Pub. No. WO83/02946 PCT Pub. Date Sep. 1, 1983.According to the invention, the antitumor agent such as daunorubicin and a well-defined quantity of a bifunctional crosslinking agent, such as glutaraldehyde, are brought together. A form of polymeric product is obtained, which is insoluble in aqueous media but which, on being resuspended in an aqueous medium in the absence of glutaraldehyde, gradually releases the antitumor agent in a soluble form, preserving its antitumor activity. Improvement of the conditions of treatment with antitumor agents. |