| 摘要 |
NEW MATERIAL:The compound of formula I [R is group of formula II-formula IV (Y is O or S; R<1> is 1-10C aliphatic hydrocarbon group or 1-10C fluorine- containing aliphatic group; R<2> and R<3> are 1-10C aliphatic hydrocarbon group or together with N atom form a 2-5C heterocyclic group); X is 1-10C alkyl, halogen, NO2, etc.]. EXAMPLE:2-Diethylamino-3-fluoro-4-methyl-1,5-benzodiazepine. USE:Antianxiety agent or its synthetic intermediate. PREPARATION:The compound of formula I wherein R is group of formula II can be produced by reacting 4-chloro-3,4,4-trifluoro-2-butanone with an amine of formula R2N (R is alkyl) and reacting the resultant compound of formula V with an o-amino(thio)phenol of formula IV.
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