| 摘要 |
<p>16757 TITLE OF THE INVENTION Tc99m-PHENIDA, RADIOSCINTIGRAPHIC AGENT FOR DIAGNOSIS OF HEPATOBILIARY DISEASE This invention relates to novel derivatives of imino diacetic acid of the formula: wherein R1 is selected from the group consisting of: - 2 - 16757 wherein X is halo (chloro, bromo or iodo) and R2 is lower alkyl of from 1-5 carbon atoms. It also relates to a novel diagnostic kit for heptaobiliary imaging comprising ingredients employed in the intravenous injection of a complex of technetium 99m, and an imino diacetic acid of the above formula. It also relates to a Process for preparing said compounds by reaction of nitrilotriacetic acid anhydride and an amine of the formula R1NH2 wherein R1 is as defined hereinabove.</p> |
