| 摘要 |
This invention encompasses prostaglandins of the formula I <IMAGE> I wherein R represents hydrogen or lower alkyl containing 1 to 6 carbon atoms; X represents -CH2-, -CH=CH-, -C 3BOND C-, -CH2-C 3BOND C-, -CH2-CH=CH- -CH2-CH2-CH2, -CH=CH-CH2-, -C 3BOND C-CH2-; and R1 represents cyclopropyl, cyclobutyl, cyclopentyl, 1-methylcyclopropyl or 1-methylcyclobutyl or XR1 together represent 1-methyl-1-cyclopropylethyl or 1-methyl-1-cyclobutylethyl; and R2 is lower alkyl having 1 to 4 carbon atoms or vinyl or ethynyl; the wavy line represents optional R or S sterochemistry These compounds are potent antisecretory agents.
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