TABLETT MED FORDROJD FRIGORING AV TEOFYLLIN

摘要

Non-disintegrating tablets containing at least 95% by weight theophylline having a pair of opposing substantially planar surfaces and a very thin cross-section (i.e. 2.03-3.05 mm) have a high bioavailability on ingestion and a relatively steady release rate permitting a 12 hr. dosing interval for maintenance of non-toxic therapeutic blood theophylline concentrations. Excipients or tableting aids are not required, but trace amounts of a tableting lubricant are preferably included to facilitate continuous large scale production.