PROCESS FOR ENZYMATIC OR MICROBIAL REACTION

摘要

PURPOSE:To enable the separation of reaction product simultaneous to the reaction while keeping high conversion, by using a reactor wherein a non- aqueous solution phase and a water phase are separated into upper and lower layers and mixing both phases near their interface. CONSTITUTION:In a reactor 1 containing a non-aqueous solution phase and a water phase separated from each other into upper and lower layers, the non- aqueous solution phase and the water phase are mixed together near the interface remaining an unmixed part of the non-aqueous solution phase and the water phase e.g. by using a stirring blade 20 in a draft tube 3. The non-aqueous solution and water as a substrate or a substrate existing in the non-aqueous solution phase and/or the water phase is converted to the objective product with an enzyme or microorganism and the product is separated from the unmixed non-aqueous solution phase and/or the water phase. The process enables the separation of the product simultaneous to the conversion of the substrate to the product and facilitates the control of various reaction conditions and the continuous operation of the reaction.