RECEPTOR-TARGETED DRUG DELIVERY SYSTEMS

摘要

Drug carrying such as liposomes and nanoparticles may be targeted to specific tissues or organs of the body by covalent attachment of therapeutic and pharmacologic ligands which retain high affinity for their receptors as well as retaining pharmacological activity. The ligands may be conjugated to monomers before they are assembled into the liposome or nanoparticle type structure. Drugs which may be carried by these carrying agents may be therapeutic or diagnostic materials.