| 摘要 |
PURPOSE:To easily produce microspheres having uniform particle size, high sphericity and excellent porosity at a low cost, by dispersing an organic solvent solution of an organic acid ester of cellulose in an aqueous medium and hydrolyzing the ester in the presence of a specific hydrolysis promoter. CONSTITUTION:A solution of an orgnic acid ester of cellulose (e.g. cellulose diacetate, cellulose triacetate, etc.) in an organic solvent (e.g. methylene chloride) is dispersed and an aqueous medium (e.g. water, an aqueous solution of gelatin, etc.) to form minute droplets of said ester solution in the aqueous medium and the ester in the droplet is hydrolyzed with an alkali (usually NaOH, etc.) in the presence of a hydrolysis promoter selected from a quaternary ammonium salt (e.g. benzyltrimethyl ammonium), its hydroxide and a water-soluble ether. USE:Suitable as a carrier for chromatography, etc.
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