| 摘要 |
<p>A novel sulfone compound represented by the general formula (I) <IMAGE> (I) wherein R1 is cyclohexyl, phenyl; or a phenyl substituted with a group selected from nitro, C1-C3 alkyl, C1-C3 alkoxy and halogen; R2, R3, R4 and R5 are respectively hydrogen, halogen, cyano or carbonyl, wherein R1 and R2 may form an o-phenylene or an o-phenylene substituted with at least one group selected from nitro C1-C3 alkyl, C1-C3 alkoxy and halogen; X is oxygen or methylene; Y is -(CH2)n-, wherein n is an integer of 0, 5 or 6, or <IMAGE> wherein m is an integer 1-3; R6 is hydrogen, C1-C3 alkyl, omega -alkylaminoalkyl, wherein each alkyl has 1-3 carbon atoms, or omega -dialkylaminoalkyl, wherein each alkyl has 1-3 carbon atoms; R7 is hydrogen or C1-C3 alkyl; and R6 and R7 may form a ring together with N, or <IMAGE> wherein R8 is hydrogen, C1-C3 hydroxyalkyl or phenyl; or a pharmaceutically acceptable salt thereof is disclosed. The compound has anti-ulcer effect.</p> |
