发明名称 TUMOR NECROSIS FACTOR FORMING INDUCER
摘要 PURPOSE:The titled inducer comprising flavonoid as an active ingredient. CONSTITUTION:A tumor necrosis factor forming inducer containing flavonoid (derivative having skeleton of flavone, flavanone, flavane, chalcone, catechin, etc.: compound widely distributing in plant, such as naringin, hesperidin, etc.). The inducer is usable as any oral or parenteral drug. A dose is 0.003-300mg/ person, preferably 0.01-30mg/person. EFFECT:Since the drug has quick sensitization time as a primary irritant, a second irritant can be early administered and TNF production can be induced at an early period. The drug has low toxicity and readily pharmaceutically manufactured. Further being relatively inexpensively and readily obtainable, the drug can be widely used.
申请公布号 JPS62273915(A) 申请公布日期 1987.11.28
申请号 JP19860118919 申请日期 1986.05.23
申请人 ZENYAKU KOGYO KK 发明人 TAKASE MUNEAKI;YASUI SOUSUKE;TAKAYANAGI HIROSHI;MORIKAWA KAORU;OSHIMA HARUYUKI;MIZUNO DENICHI
分类号 C07H17/07;A61K31/35;A61K31/352;A61K31/70;A61K31/7042;A61K31/7048;A61P35/00;A61P43/00;C07D311/26 主分类号 C07H17/07
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