N-1 subsituted sulfonylaminocarbonyl, C-4 substituted monobactams.

摘要

This invention presents novel 2-azetidinone compounds as shown in formula I, which are useful as antibacterial agents to eradicate or control susceptible microbes. These compounds have a (5-hydroxy-4-pyridone-2-yl)carbonylamino-1-(2-imidazolidone-3-yl)sulfo nylaminoca rbonyl group at the N-1 position, and a carbonate-type substituent or an amino acid derivative at the C-4 position via an ester linkage. Intermediates and processes for making these compounds are also disclosed.