发明名称 Dopamine-beta-hydroxylase inhibitors.
摘要 <p>Compounds of Formula : &lt;CHEM&gt; in which n is 0 to 5, R is hydrogen or C1-4alkyl and X is hydrogen, halo, C1-4alkyl, CN, NO2, SO2NH2, COOH, CHO, OH, CH2OH, C1-4alkoxy, CF3, SO2CH3, SO2CF3 or CO2CaH2a+1 wherein a is 1 to 5 or any synthetically accessible combination thereof of up to 5 substituents or any pharmaceutically acceptable salt or hydrate thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy as dopamine beta -hydroxylase inhibitors.</p>
申请公布号 EP0246888(A2) 申请公布日期 1987.11.25
申请号 EP19870304504 申请日期 1987.05.20
申请人 SMITHKLINE BEECHAM CORPORATION 发明人 FINKELSTEIN, JOSEPH ALAN;KRUSE, LAWRENCE IVAN
分类号 A61K31/41;A61P1/04;A61P7/10;A61P9/04;A61P9/08;A61P9/12;A61P43/00;C07C67/00;C07C239/00;C07C281/02;C07C301/00;C07C303/40;C07C311/37;C07C313/00;C07C315/04;C07C317/32;C07C325/00;C07C337/06;C07D249/12;(IPC1-7):C07D249/12;C07C159/00;C07C133/02 主分类号 A61K31/41
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