摘要 |
This invention relates to novel aroylated derivatives of pyrrole. More particularly it provides the novel naphthoyl derivatives of pyrrolyl-2-carboxylic acid having the general formula I: <IMAGE> wherein: R1 is a lower alkyl radical, a phenyl radical or a hydrogen; X is a hydrogen, a hydroxy or a methylsulphinyl group; Y is a hydrogen or together with A' a double bond; A is a hydrogen or a hydroxy; A' is a hydrogen or together with Y a double bond; B is a hydrogen or a hydroxy; B' is a hydrogen or together with C a double bond; C is a hydrogen or together with B' a double bond; C' is a hydrogen, a hydroxy or a methylsulphinyl group; with the proviso that X, Y, A, A', B, B', C and C' are not simultaneously a hydrogen. The compounds according to this invention, may exist in the free acid form or as a salt. They found a use in human or veterinary medicine in the form of pharmaceutical compositions for preventing or treating the immunological diseases.
|