4181-2 SUBSTANCE AND ACYL DERIVATIVE THEREOF

摘要

NEW MATERIAL:A compound shown by the formula (R is H or acyl). USE:An anti-cancer drug and a carcinostatic agent. PREPARATION:For example, a bacterium capable of producing 4181-2 substance is cultivated. For example, Streptomyces sp. 4181 (FERM P-1010) is cultivated under an aerobic condition by aerated spinner culture method, etc., preferably at acidity - about neutrality at 27-30 deg.C for 2-5 days.