发明名称 Alkenamide derivatives.
摘要 <p>The invention concerns novel N-[4(Z)-2-substituted-6-(4-o-hydroxyphenyl-1,3 dioxan-cis-5-yl) hexenoyl]sulphonamide derivatives of formula I of value as therapeutic agents. Typically R&lt;1&gt; is a branched (3-6C)alkyl, trifluoromethyl or phenyl radical as defined hereinafter and R&lt;2&gt; is alkyl, benzyl or phenyl. The invention also discloses salts of the formula I compounds as well as pharmaceutical compositions containing the compounds and processes for the production of the compounds.</p>
申请公布号 EP0246002(A2) 申请公布日期 1987.11.19
申请号 EP19870303832 申请日期 1987.04.29
申请人 IMPERIAL CHEMICAL INDUSTRIES PLC 发明人 BROWN, GEORGE ROBERT;SMITHERS, MICHAEL JAMES
分类号 A61K31/335;A61K31/357;A61P9/00;A61P9/12;A61P11/08;C07D319/06;C07F7/18 主分类号 A61K31/335
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