发明名称 |
EDTA-free heparins, heparin fractions and fragments, processes for their preparation and pharmaceutical compositions containing them. |
摘要 |
<p>Heparins, heparin fractions or fragments, optionally salified with pharmaceutically acceptable cations, having molecular weight ranging from 1.000 to 30.000 D, characterized by an EDTA content lower than 0.1%, by the absence, in the <1>H-NMR spectra, of the signals due to EDTA between 2.50 and 4.00 p.p.m. and substantially free from bleeding effect and optionally free from signals, in the <1><3>C-NMR spectrum, from 80 to 86 p.p.m.</p> |
申请公布号 |
EP0245813(A2) |
申请公布日期 |
1987.11.19 |
申请号 |
EP19870106784 |
申请日期 |
1987.05.11 |
申请人 |
ITALFARMACO S.P.A. |
发明人 |
CASU, BENITO;ORESTE, PASQUA;NAGGI, ANNAMARIA;TORRI, GIANGIACOMO;ZOPPETTI, GIORGIO;SPORTOLETTI, GIANCARLO;DE SANTIS, FRANCESCO |
分类号 |
C08B37/10;A61K31/715;A61P7/02;C08B37/00 |
主分类号 |
C08B37/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|