| 摘要 |
PURPOSE:To obtain the titled compound useful as a surfactant, wetting agent, antistatic agent, etc., without causing foaming trouble in evacuation operation, in high yield, by acylating N<2>,N<2>-dialkyllysine with a long-chain carboxylic acid halide. CONSTITUTION:The objective compound of formula II can be produced by acylating an N<2>,N<2>-dialkyllysine of formula I (R<1> and R<2> are 1-4C alkyl) with a long-chain carboxylic acid halide of formula R<3>COX (R<3> is 5-20C alkyl or alkenyl; X is halogen) (e.g. lauroyl chloride) in a mixed solvent of acetonitrile and water in the presence of a base (e.g. NaOH) at room temperature. The amount of the long-chain carboxylic acid halide is 0.8-1.5mol per 1mol of the compound of formula I and the base is used in excess to keep the pH of the reaction system to 7-14. The volume ratio of the acetonitrile to water in the solvent is 3:7-9:1 and the amount of the solvent is 10-30pts.wt. per 1pt.wt. of the compound of formula I.
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