| 摘要 |
NEW MATERIAL:The compound of formula I [R<1> and R<2> are H, halogen, trifluoromethyl, OH, amino, nitro, cyano, 1-4C alkyl, 1-4C alkoxy or 2-5C alkanoylamido; R<3> is H, 1-8C alkyl, 1-4C hydroxyalkyl, 2-5C alkanoyloxy-1-4C alkyl, pyridyl, (substituted) aryl-1-4C alkyl or (substituted) aryl; n is 0-2, the dotted line between 4-position and 4ae-position is single or double bond]. EXAMPLE:2-(4-Chlorophenyl)-2,3,4,4a-tetrahydro-5H-(1)benzothio-pyrano-[ 4,3-c]py ridazin-3-one. USE:An antianxiety agent. PREPARATION:The objective compound can be produced by the cyclization reaction of the compound of formula III produced by reacting the compound of formula II with the hydrazine derivative of formula R<3>-NHNH2, etc.
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