| 发明名称 |
2-Vinylpenams and process. |
| 摘要 |
<p>6 beta -(L- alpha -Aminoadipoyl)-2 alpha -vinyl-2 beta -methylpenam-3-carboxylic acid is provided in an enzymatic process converting delta -(L- alpha -aminoadipoyl)-L-cysteinyl-D- gamma , delta -didehydroisoleucine with isopenicillin N synthetase. The 2 alpha -vinylpenam product is converted by known methods to the 6 beta -amino-2 alpha -vinyl-2 beta -methylpenam-3-carboxylic acid nucleus and the latter is N-acylated to provide corresponding 6 beta -acylaminopenams.</p> |
| 申请公布号 |
EP0244195(A1) |
申请公布日期 |
1987.11.04 |
| 申请号 |
EP19870303725 |
申请日期 |
1987.04.28 |
| 申请人 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD |
发明人 |
BALDWIN, JACK EDWARD |
| 分类号 |
C12P17/18;A61K31/43;A61P31/04;C07D499/00;C07D499/04;C07D499/42;C07D499/44;C07D499/60;C07D499/64;C07D499/70;C07D499/72;C07D499/76;C07D499/78;C12P37/00;(IPC1-7):C12P37/00 |
主分类号 |
C12P17/18 |
| 代理机构 |
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代理人 |
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| 地址 |
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