发明名称 |
Hematology control compositions for three populations of leukocytes; and methods for their preparation and use in whole blood control systems |
摘要 |
This invention primarily is directed to a hematology reference control solution, the three separate white cell control portions thereof consisting of three types of fixed red cells of determined size distribution for checking the operation of a particle analyzing instrument, including its predetermined lower and upper threshold settings for each class or subclass of leukocytes. For preparing a human granulocyte analogue, nurse shark erythrocytes are altered and fixed in a chilled solution to simulate in number, size and distribution the granulocytes in human whole blood. Such a granulocyte analogue is useful as a free-standing reference control, for determination of human granulocytes only, or can be comingled with reference controls for lymphocytes and mononuclear cells for use with multi-parameter instruments to give a trimodal leukocyte reference control, which itself can be included in a multiple-analysis hematology reference control, having components for also determining red blood cell and platelet parameters.
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申请公布号 |
US4704364(A) |
申请公布日期 |
1987.11.03 |
申请号 |
US19840612091 |
申请日期 |
1984.05.18 |
申请人 |
COULTER ELECTRONICS, INC. |
发明人 |
CARVER, FRANKLIN J.;GERULA, THEODORE J. |
分类号 |
G01N33/48;G01N33/96;(IPC1-7):G01N31/00 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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