发明名称 FORFARANDE FOR FRAMSTELLNING AV KETAL OCH TIOKETALDERIVAT AV MERKAPTOACYLPROLINER
摘要 Mercapto acyl compounds, having hypotensive activity, have the formula:- <IMAGE> or are salts thereof, wherein R is hydrogen or lower alkyl, R1 and R2 are various defined organic groups or R1 and R2 together complete a ring, X1 and X2 are oxygen or sulphur, one of p and q is 1 and the other is 1 or 2, R3 and R4 are hydrogen lower alkyl, lower alkyl thio, -(CH2)n SH or halo lower alkyl, (n being from 1 to 3), R6 is hydrogen or (when R3 is lower alkyl) lower alkyl, m is 0, 1 or 2 and R5 is hydrogen or a protecting group.
申请公布号 SE451839(B) 申请公布日期 1987.11.02
申请号 SE19790010550 申请日期 1979.12.20
申请人 E R SQUIBB & SONS INC 发明人 J * KRAPCHO
分类号 A61K31/40;A61K31/401;A61K31/4025;A61P9/12;C07D207/16;C07D401/12;C07D405/12;C07D409/12;C07D491/10;C07D491/113;C07D495/10;C07D497/10;(IPC1-7):C07D207/10 主分类号 A61K31/40
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