| 摘要 |
The present invention relates to quinoline derivatives of the formula <CHEM> wherein Z is an amino group or a halogen atom, <CHEM> in which R1 is a hydrogen atom, a lower alkyl or haloalkyl group, R2 is a hydrogen atom or a lower alkyl group, R3 is a lower alkyl or haloalkyl group, R4 is a hydrogen atom or a lower alkyl group, R5 and R6 are the same or different and each represents a hydrogen atom or a lower alkyl group, or R5 and R6, together with the nitrogen atom to which they are attached, form a heterocyclic ring, and n is 0 or 1, with the proviso that when Z is an amino group R is (B); and esters thereof and salts thereof and processes for preparation thereof. These compounds show excellent antbacterial activity and are useful antibacterial agents. |
