| 摘要 |
The compound of the formula I <IMAGE> has calcium antagonist properties and is used as a medicament. The substituents in the formula have the following meaning: R(1) and R(4) are H, alkyl, alkoxy, halogen, CF3, NO2, OH, acetamido or amino, R(2) is H, alk(en)yl or phenylalkyl; R(3) is H, (cyclo)alk(en)yl, cycloalkylalkyl, phenyl or phenylalkyl; A is (CH2)1-4X-(CH2)0-3 where X = CH2, O, S, CO, CHOH or CR(5)R(5)'; and R(5) is H or alkyl; B is a series of (di)amines, T is (CH2)0-3; D is CHOH, CO, NR(10)CO, CONR(11) or O; E is (CH2)0-3; F is a bond, NR(12)CO, CONR(13), CO or O; G is phenyl or furyl; R(6), R(7), R(8) and R(9) are H, alkyl, (phenyl)alkanoyl, phenylalkyl, benzhydryl(alkyl) or benzyl; and R(10), R(11) and R(12) are H or alkyl. |
