发明名称 |
PARTIALLY PRUIFIED BONE-INDUCING FACTOR |
摘要 |
Two polypeptide factors that are found in bone and that have chondrogenic/osteogenic activity and TGF- beta activity are described. Each has a molecular weight of approximately 26,000 daltons by SDS-PAGE. Each reduces to a single polypeptide indicating that the factors are probably homodimers. One has an N-terminal sequence identical to that of human placenta-derived TGF- beta , whereas the other has an N-terminal sequence that is different from that of TGF- beta derived from human placenta. The two factors are purified to homogeneity using RP-HPLC or acetic acid-urea gel electrophoresis. |
申请公布号 |
AU5649586(A) |
申请公布日期 |
1987.10.29 |
申请号 |
AU19860056495 |
申请日期 |
1986.04.22 |
申请人 |
COLLAGEN CORP. |
发明人 |
SAEID SEYEDIN;THOMAS THOMAS |
分类号 |
B65B25/14;A61K35/32;A61K38/00;A61L27/22;B64C11/00;B65B35/50;B65H31/08;B65H31/12;C07K1/18;C07K1/20;C07K1/26;C07K1/34;C07K14/00;C07K14/495;C07K14/52 |
主分类号 |
B65B25/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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