发明名称 1-Substituted Alkyl-1, 2-Dihydro-2-Pyrazinone derivatives.
摘要 <p>Compounds of formula (I) &lt;CHEM&gt; wherein R is hydroxyl, halogen, lower alkanoyloxy, R4-carbamoyloxy, arylthio, 1-methyltetrazole-5-yl-thio, 1-imidazolyl, morpholino, &lt;CHEM&gt; in which R4 is lower alkyl or aryl, R5 is hydrogen, lower alkyl or aryl, R6 is hydrogen, lower alkyl, hydroxy-lower alkyl, aryl, aryl-lower alkanoyl, arylcarbonyl, arylsulfonyl or thienyl-lower alkanoyl, A and A1 are lower alkylene, m is an integer of from 4 to 6, n is the integer 2 or 3; R1 is alkyl aryl-lower alkyl or aryl; and R2 and R3 are each lower alkyl or together constitute tetramethylene; and pharmacologically acceptable non-toxic salts thereof; wherein aryl means phenyl unsubstututed or substituted by C1-3 alkyl, halogen, nitro or lower alkoxyl; have an inhibitory action on platelet aggregation, vasodilating activity and/or inhibitory action on lipoperoxide generation.</p>
申请公布号 EP0242957(A1) 申请公布日期 1987.10.28
申请号 EP19870301680 申请日期 1987.02.25
申请人 TOYO JOZO KABUSHIKI KAISHA 发明人 YASO, MASAO;SUZUKI, YUKIO;SHIBATA, KENSUKE;HAYASHI, EIICHI
分类号 C07D243/00;A61K31/495;A61K31/535;A61K31/55;A61P3/06;A61P7/02;A61P9/08;C07D241/18;C07D241/44;C07D247/00;C07D333/00;C07D401/06;C07D403/06;C07D403/12;C07D409/12;C07D521/00;(IPC1-7):C07D241/18 主分类号 C07D243/00
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