Adsorbent for chromatography, method of producing the same, and column system for chromatography.

摘要

In an adsorbent for use in chromatography comprised of secondary particles (B2) formed by aggregation of primary particles in the form of fine crystals of hydroxyapatite, the aggregated primary particles are sintered so as to be bonded together. The adsorbent is produced by heating the secondary particles (B2) at a temperature not lower than 300 DEG C and not higher than the decomposition temperature, and has significantly improved repetitive using properties. In a column system for use in chromatography, there are provided a main column (K1) packed with the above described adsorbent and a precolumn (K2) packed with a second adsorbent comprised of conventional hydroxyapatite particles. This column has also a significantly improved repetitive using properties.