发明名称 |
USE OF 1,4-DIHYDROPYRIDINES IN ANTIARTERIOSCLEROTIC AGENTS AND THEIR PREPARATION |
摘要 |
<p>Use of 1,4-dihydropyridines in antiarteriosclerotic agents and their preparation A method of countering arteriosclerosis in a patient comprising administering to such patient an antiarteriosclerotic effective amount of a 1,4-dihydropyridine of the formula < IMG > in which R1 and R2 each independently is alkyl or alkoxyalkyl having up to 12 C atoms, the alkyl radical optionally being substituted by fluorine or chlorine, and R3 is one or two substituents independently selected from the group comprising nitro, trifluoromethyl, halogen and cyano. The material is effective even upon oral administration.</p> |
申请公布号 |
CA1228549(A) |
申请公布日期 |
1987.10.27 |
申请号 |
CA19830430227 |
申请日期 |
1983.06.13 |
申请人 |
BAYER AKTIENGESELLSCHAFT |
发明人 |
SEUTER, FRIEDEL;BOSSERT, FRIEDRICH;MEYER, HORST;WEHINGER, EGBERT;BOESHAGEN, HORST |
分类号 |
A61K31/435;A61K31/455;A61P9/10;A61P43/00;C07D211/90;(IPC1-7):A61K31/455 |
主分类号 |
A61K31/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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